LABEX TOUCAN
Toulouse Cancer Laboratory of Excellence
The Toulouse Cancer Laboratory of Excellence is a project that aims to understand the mechanisms of resistance and relapse in blood cancers and
by extension in certain solid cancers.
teams and platforms
Team
S. PYRONNET
AND F. MEGGETTO
R’n Blood :
RNA Biology In Hematologic Tumors
Team
C. LAURENT
NoLymIT :
New Immunotherapies Against Lymphoma
TEAM
H. AVET-loiseau
et l. martinet
GENIM :
Genomic And Immunology Of Myeloma
team
J.E. SARRY
METAML :
Metabolism And Therapeutic Resistance In Acute Myeloid Leukemia
Team
S. VALITUTTI
DynAct :
Molecular Dynamics Of Lymphocyte Interactions
TEAM
J.P. GIRARD
Vascular biology
Endothelial cells in Immunity, Inflammation and Cancer
PLATFORM
IMAG’IN
Labelled Ibisa
Imag’IN is a technological platform offering its expertise for the study, implementation and analysis of projects involving histopathology, functional anatomy and biological imaging techniques.
In particular, we have recognised expertise in virtual microscopy and image analysis.
Team
BIOINFORMATICs IUCT
Bioinformatics Unit
IUCT – CRCT
The bioinformatics platform of the Toulouse University Cancer Institute (IUCT) and the Toulouse Cancer Research Centre (CRCT) is made up of 12 bioinformaticians, statisticians and computer engineers with multidisciplinary expertise to handle the data generated by the various sequencing, cellular and tissue imaging platforms for research units (CRCT) and the hospital (IUCT) in routine practice. This work is based on a very high-speed computing cluster, GPUs and the development of innovative computing solutions.
THE LABEX
To find biomarkers of resistance in haematopoietic cancers and potential therapeutic targets to circumvent this resistance.
CHALLENGE
RESEARCH
AXIS
Deciphering drug resistance in anaplastic large cell lymphomas expressing the oncogenic tyrosine kinase ALK.
Mapping γδT cells and vasculature in lymphoma: a single-cell study for the localization and functional characterization of cytolytic T cells infiltrating human lymphomas.
Immunometabolic landscape of myeloma associated with the efficacy of anti-CD38 mAbs.
Mitochondrial metabolism supports inhibitor resistance of IDH mutants in acute myeloid leukemia.
ALK-transformed mature T cells restore the characteristics of early thymus progenitors.
FAK activity in cancer-associated fibroblasts is a prognostic marker and a key metastatic drug player in pancreatic cancer
results
THE LABEX IN FIGURES
ENGINEERS & TECHNICIANS
DOCTORAL STUDENTS
RESEARCHERS & PERMANENT RESEARCH TEACHERS
HOSPITAL PRACTITIONERS
LABEX & TRAINING
CARe Graduate School aims to train master and doctoral students in the field of cancer, ageing and rejuvenation.
The Phd Program within the CRCT complements this teaching by inviting students to participate in scientific animation.
Watch the video of the CARe programme here.
PARTNERSHIPS & FUNDING
ACADEMIC AND HOSPITAL PARTNERS
FINANCIAL SUPPORT FOR THE TOUCAN LABEX PROGRAM
LIVE
CRCT-Oncopole Follow 1,433 1,279
Compte officiel du Centre de Recherches en Cancérologie de Toulouse
;
🇬🇧Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells. ImPact team @CordelierPierre article from @crctoncopole published in @CommsBio
➡️https://www.crct-inserm.fr/en/targeting-the-energy-production-process-in-pancreatic-cancer-cells-which-relies-on-an-enzyme-called-cytidine-deaminase-could-make-these-cells-more-vulnerable/
Toulouse Cancer Research Center (Oncopole)
Toulouse - FR
CRCT-Oncopole Follow 1,433 1,279
Compte officiel du Centre de Recherches en Cancérologie de Toulouse
🇬🇧Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells. ImPact team @CordelierPierre article from @crctoncopole published in @CommsBio
➡️https://www.crct-inserm.fr/en/targeting-the-energy-production-process-in-pancreatic-cancer-cells-which-relies-on-an-enzyme-called-cytidine-deaminase-could-make-these-cells-more-vulnerable/
Contact us
+33 5 82 74 15 75
Want to join
the CRCT team ?
