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The PI3K alpha inhibition sensitizes ovarian cancer with PIK3CA mutation to conventional chemotherapy
Transipedia : project for sequences large-scale exploration and its application in cancer
Prevention of resistances to targeted therapies in lung cancer with a new therapeutic combination.
New publication on Autophagy
An oncolytic virus with strong appetence for the most aggressive type of pancreatic cancer cells
The Enzyme Cholesterol-5,6-Epoxide Hydrolase: A Key Regulator in Various Diseases
Kartezio: a fully transparent AI-based approach to biomedical image analysis
Autophagy contributes to resistance to ruxolitinib in myeloproliferative neoplasms
Cancer under pressure: which signals are activated?
The level of von Willebrand factor is a pronostic marker in patients with metastatic melanoma treated by immune checkpoint inhibitors
Fabienne Meggetto awarded by the Amgen France Fund
Preclinical development of non-viral gene therapy for patients with advanced pancreatic cancer
Single-cell spatial explorer a software to to analyse the cells characteristics in relation with their position in any kind of biological tissue
Pancreatic cancer cell and gene biotherapies; past, present and future
Fighting bronchial cancers
Deregulation of protein synthesis in pancreatic cancer
Identity theft by natural killers : NK cells steal PD-1 from tumor cells via trogocytosis
A cholesterol derivative to produce reprogrammed tumour exosomes that activate the immune system against tumours
Web database about RNA structures called RNA G-Quarduplexes and their interaction with RNA binding proteins
Dendrogenin A reprograms tumor cells to secrete exosomes which activate the immune system against cancer
Presentation of the CREFRE UMS006 Inserm phenotyping service
An intermediate level of genetic instability of the tumor is more favorable to an increase in tumor aggressiveness than a low or very high level
Identification of therapeutic targets and repositioning of drugs against COVID-19 through the analysis of interaction networks between proteins, drugs, pathologies and symptoms
The CRCT and the IUCT-o will participate in the INTREPIDS project
The value of screening for DPD activity in all patients treated with fluoropyrimidines.
The PACMINE project is selected for the Toulouse Cancer Health Foundation’s call for funds
Study of the Interplay effect in Radiotherapy using Monte-Carlo methods.
Overexpression of the oncogenic long non-coding RNA LONA in acute myeloid leukaemia and changes in its cellular localisation by the NPM1c+ mutant protein.
Targeted therapies straight to the point or how to counter the defence of cancer cells in response to these therapies?
Myeloid leukaemia: understanding treatment resistance to move towards personalised medicine
In search of the cells that cause pediatric leukemia.
Role of Vps34, presentation at the 2nd Young Scientist Cancer Congress
Targeting the energy production process in pancreatic cancer cells, which relies on an enzyme called cytidine deaminase, could make these cells more vulnerablen ligase TRIP12 is required for pancreatic acinar cell plasticity and the development of pancreatic cancer.
Intraepithelial tumor-infiltrating lymphocytes shape loco-regional PET/CT spread of locally advanced cervical cancer.
TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
Cytidine deaminase confers resistance to DNA-damaging drugs
Roxana Khazen, winner of the ARC Foundation’s call for “passerelle” projects
A new MRI technique can locate foci of aggressive tumour cells and could improve the treatment of glioblastoma
CD36 drives metastasis and relapse in acute myeloid leukemia
Cancer: a key mechanism for improving immunotherapies identified by a Toulouse team
Encouraging phase 1 results of hypofractionated stereotactic re-irradiation in combination with Durvalumab in recurrent Glioblastoma.
A new target to fight certain aggressive leukaemias
Acquired genetic abnormalities predict outcome in patients with GATA2 deficiency
How to target PI3Ks 3 classes in cancer?
Resisting T cell attack: tumor-cell-intrinsic defense and reparation mechanisms.
The Roland Garigou Foundation for Culture & Health awards several prizes and grants to the CRCT in 2022
Integrative single-cell multi-omics analyses to understand Leukemia resistance.
Loélia Babin Young Talent Award 2022 of the L’Oréal Foundation for Women in Science
Analysis of circular RNAs by the Oxford Nanopore long-read sequencing platform
Design of an intracellularly acting antibody blocking the RHOA family of proteins to study a cellular process involved in carcinogenesis.
Cholesterol is involved in ageing processes
Impact of co-administration of two amino acid solutions on the elimination and adverse effects of 177Lu-Dotatate
The Roland Garigou Foundation for Culture & Health awards several prizes and grants to the CRCT
Protocol for selecting antibodies that degrade their antigen in cells.
Real-time analysis of replication and activity of oncolytic viruses in pancreatic cancer
A new immunotherapy strategy for melanoma patients.
Rapid detection of a cancer biomarker by a microfluidic chip
PI3K proteins sense mechanical forces in tumours.
GAMMORA: a tool to automatically prepare radiotherapy simulations
Laura Poillet-Perez Young Talent Award 2021 of the L’Oréal Foundation for Women in Science
Role of autophagy in response to targeted therapy in ALK+ lymphoma
The rapid progression and poor prognosis of pancreatic cancer: a therapeutic lead.
Exploring biological characteristics of lung cancer in each patient gives clues on differences in the way the patient’s immune system fights against the tumour
The E3 ubiquitin ligase TRIP12 is required for pancreatic acinar cell plasticity and the development of pancreatic cancer.
The regulation of mRNA translation by RNA G-quadruplex structures contributes to cancer progression and resistance to treatment
Human genetic defects of sphingolipid synthesis
Study of the contribution of tumour lipids to the metastatic progression of cutaneous melanoma
Identification and characterisation of the cells responsible for the initiation of B-lineage leukaemias
Surface-guided radiotherapy overview: Technical aspects and clinical applications.
A computational model of the formation of cells limiting the effect of promising cancer therapies
The power of the intestine against metastases
Dr Marc Poirot is laureate of the Schroepfer Prize 2023
Recent discoveries on the cholesterol metabolic pathway
Top 5 CRCT publications for the year 2022
Lessons from the melanoma ecosystem
Towards a new approach to immunotherapy in the treatment of skin cancers
Welcome to the Brain Galaxy
Jean-Emmanuel Sarry receives the Guy Lazorthes Prize of the Academy of Sciences 2022
Heterogeneity in long-term outcomes for R-ISS stage II in newly diagnosed multiple myeloma patients
Obesity and melanoma: a new link
Diversity in rRNA 2’Ome profiles in cancer and impact on translational regulation
NeoVirTech SAS opens a new laboratory at the Cancerology Research Center of Toulouse (CRCT)
TLR7 agonists have dual effect on pancreatic tumors that jeopardize their use in clinics
Role of genetic mutations in trabectedin liver toxicity.
Normalization of protein secretions in the tumor microenvironment blocks metastasis in pancreatic cancer
Rapid and sensitive detection of biomarkers of interest in cancerology
The cell signalling enzymes PI3Kalpha and PI3Kβ play major roles in the body.
Reprogramming a family of lipids to increase the effectiveness of melanoma immunotherapy.
Première saison des Apprentis Chercheurs au CRCT
CRCT Laureate Wins Laurette Fugain Award 2021
Targeting a family of proteins important for cancer development using intracellular macromolecules
From circular RNA to circular RNA derived from chromosomal translocations in hematological malignancies
Toulouse Cancer Research Center (Oncopole)
Toulouse - FR
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